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8th International Conference on Advanced Computing and Communication Systems, ICACCS 2022 ; : 1649-1653, 2022.
Article in English | Scopus | ID: covidwho-1922647

ABSTRACT

Coronavirus flare-up chances human existence and it challenges the general wellbeing. Hand cleanliness, an extremely basic activity, is very much acknowledged to be one of the essential methods of decreasing medical care-related disease and of improving patient security. These days wearing masks, utilizing hand sanitizers, checking temperatures are being done in all places, and so forth yet at the same time in many spots individuals utilize conventional sanitizer gadgets which build the spread of microorganisms. Normally an individual is in charge of observing the body temperature and sanitizer level by taking a chance with his life. This survey Internet of Things (IoT) based hand sanitizer dispenser with temperature and level monitoring distinguishes the presence of the people and gives out alerts in form of the human voice to sanitize their hands if the dispenser goes unrecognized. Furthermore, we have a contactless sanitizer dispenser to stay away from contact among humans and dispensers which will keep us away from the further spread of infection and microorganisms. © 2022 IEEE.

2.
Appl Biochem Biotechnol ; 194(1): 291-301, 2022 Jan.
Article in English | MEDLINE | ID: covidwho-1748423

ABSTRACT

Corona virus pandemic outbreak also known as COVID-19 has created an imbalance in this world. Scientists have adopted the use of natural or alternative medicines which are consumed mostly as dietary supplements to boost the immune system as herbal remedies. India is famous for traditional medicinal formulations which includes 'Trikadu'-a combination of three acrids, namely Zingiber officinale, Piper nigrum and Piper longum which have antioxidant properties that boost our immune system hence acting as a strong preventive measure. In this study, AutoDock 4.0 was used to study interaction between the phytocompounds of Trikadu with RNA-dependent polymerase protein and enveloped protein of the SARS-CoV-2 virus. Analysis of the results showed that coumarin, coumaperine and bisdemethoxycurcumin showed strong bonding interactions with both the proteins. We can conclude that Trikadu has the potential molecules; hence, it can be incorporated in the diet to boost the immune system as a preventive measure against the virus.


Subject(s)
COVID-19 Drug Treatment , COVID-19/immunology , Phytotherapy , Plant Preparations/therapeutic use , SARS-CoV-2 , Antioxidants/isolation & purification , Antioxidants/therapeutic use , COVID-19/virology , Computer Simulation , Coronavirus RNA-Dependent RNA Polymerase/chemistry , Coronavirus RNA-Dependent RNA Polymerase/drug effects , Dietary Supplements , Ginger/chemistry , Humans , Immune System/drug effects , India , Ligands , Medicine, Traditional , Molecular Docking Simulation , Phytochemicals/chemistry , Phytochemicals/therapeutic use , Piper/chemistry , Piper nigrum/chemistry , Plant Preparations/isolation & purification , Plants, Medicinal/chemistry , SARS-CoV-2/chemistry , SARS-CoV-2/drug effects , SARS-CoV-2/immunology , Spike Glycoprotein, Coronavirus/chemistry , Spike Glycoprotein, Coronavirus/drug effects
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